Yohimbic acid ethyl ester
Yohimbic acid ethyl ester (Compound 3a) is a selective ADRA2A antagonist with an IC50 of 31 nM[1].
Product Specifications
CAS Number
73840-32-1
UNSPSC
12352005
Target
Adrenergic Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/yohimbic-acid-ethyl-ester.html
Smiles
O=C([C@@H]1[C@@]2([H])C[C@@]3([H])C4=C(CCN3C[C@]2([H])CC[C@@H]1O)C5=CC=CC=C5N4)OCC
Molecular Formula
C22H28N2O3
Molecular Weight
368.47
References & Citations
[1]Chayka A, et al. Structure-Based Drug Design of ADRA2A Antagonists Derived from Yohimbine. J Med Chem. 2024 Jun 27;67 (12) :10135-10151.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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