Boc-NHCH2-Ph-pyrimidine-NH2
Product Specifications
UNSPSC Description
Boc-NHCH2-Ph-pyrimidine-NH2 is the linker for PROTAC molecule XYD198 (HY-161498)[1].
Target Antigen
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/boc-nhch2-ph-pyrimidine-nh2.html
Solubility
10 mM in DMSO
Smiles
O=C(OC(C)(C)C)NCC(C=C1)=CC=C1C2=NC=C(N)C=N2
Molecular Weight
300.36
References & Citations
[1]Hu J, et al., Discovery of Highly Potent and Efficient CBP/p300 Degraders with Strong In Vivo Antitumor Activity. J Med Chem. 2024 May 9;67(9):6952-6986.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-161499/Boc-NHCH2-Ph-pyrimidine-NH2-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-161499/
Clinical Information
No Development Reported
CAS Number
3040121-15-8
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