Boc-NHCH2-Ph-pyrimidine-NH2
Boc-NHCH2-Ph-pyrimidine-NH2 is the linker for PROTAC molecule XYD198 (HY-161498) [1].
Product Specifications
CAS Number
[3040121-15-8]
UNSPSC
12352005
Target
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/boc-nhch2-ph-pyrimidine-nh2.html
Solubility
10 mM in DMSO
Smiles
O=C(OC(C)(C)C)NCC(C=C1)=CC=C1C2=NC=C(N)C=N2
Molecular Formula
C16H20N4O2
Molecular Weight
300.36
References & Citations
[1]Hu J, et al., Discovery of Highly Potent and Efficient CBP/p300 Degraders with Strong In Vivo Antitumor Activity. J Med Chem. 2024 May 9;67 (9) :6952-6986.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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