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HldA/E-IN-1

Product Specifications

UNSPSC Description

HldA/E-IN-1 (compound 8) is a dual inhibitor of HldA/E, with IC50 values ​​of 17.2 μM and 67.8 μM for HldA/E, respectively. HldA/E-IN-1 can be used in the study of anti-bacterial infection[1].

Target Antigen

Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/hlda-e-in-1.html

Smiles

F[C@@H](P(O)(O)=O)[C@@]1(O)[C@@H](O)[C@@H](O)[C@H](O)[C@@H]([C@H](O)COP(O)(O)=O)O1

Molecular Weight

402.16

References & Citations

[1]Cao J, et al. Exploring fluorinated heptose phosphate analogues as inhibitors of HldA and HldE, key enzymes in the biosynthesis of lipopolysaccharide. Bioorg Chem. 2024 Aug 30;153:107767.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-168061/HldA-E-IN-1-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-168061/

Clinical Information

No Development Reported

CAS Number

2593325-52-9

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