HldA/E-IN-1

HldA/E-IN-1 (compound 8) is a dual inhibitor of HldA/E, with IC50 values of 17.2 μM and 67.8 μM for HldA/E, respectively. HldA/E-IN-1 can be used in the study of anti-bacterial infection[1].

Product Specifications

CAS Number

[2593325-52-9]

UNSPSC

12352005

Target

Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/hlda-e-in-1.html

Smiles

F[C@@H](P(O)(O)=O)[C@@]1(O)[C@@H](O)[C@@H](O)[C@H](O)[C@@H]([C@H](O)COP(O)(O)=O)O1

Molecular Formula

C8H17FO13P2

Molecular Weight

402.16

References & Citations

[1]Cao J, et al. Exploring fluorinated heptose phosphate analogues as inhibitors of HldA and HldE, key enzymes in the biosynthesis of lipopolysaccharide. Bioorg Chem. 2024 Aug 30;153:107767.