Rat Factor Ixa

<strong>Rat Factor Ixa</strong>_x000D_ <strong>Catalog number:</strong> B2016613_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 25 ug _x000D_ <strong>Molecular Weight or Concentration:</strong> 45000_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> −20°C_x000D_ <strong>Keywords:</strong> Rat Factor Ixa_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong> _x000D_ 1: Jayne CL, Andreani T, Chan TY, Chelliah MV, Clasby MC, Dwyer M, Eagen KA, Fried S, Greenlee WJ, Guo Z, Hawes B, Hruza A, Ingram R, Keertikar KM, Neelamkavil S, Reichert P, Xia Y, Chackalamannil S. Discovery of hydroxy pyrimidine Factor IXa inhibitors Bioorg Med Chem Lett. 2020 Aug 1;30(15):127279. _x000D_ 2: Wong PC, Pinto DJ, Knabb RM. Nonpeptide factor Xa inhibitors: DPC423, a highly potent and orally bioavailable pyrazole antithrombotic agent Cardiovasc Drug Rev. 2002 Summer;20(2):137-52. _x000D_ 3: Xiao C, Zhao L, Gao N, Wu M, Zhao J. Nonasaccharide Inhibits Intrinsic Factor Xase Complex by Binding to Factor IXa and Disrupting Factor IXa-Factor VIIIa Interactions Thromb Haemost. 2019 May;119(5):705-715. _x000D_ 4: Ankrom W, Wood HB, Xu J, Geissler W, Bateman T, Chatterjee MS, Feng KI, Metzger JM, Strapps WR, Tadin-Strapps M, Seiffert D, Andre P. Preclinical and translational evaluation of coagulation factor IXa as a novel therapeutic target Pharmacol Res Perspect. 2016 Jan 15;4(1):e00207. _x000D_ 5: Hedner U. History of rFVIIa therapy Thromb Res. 2010 Apr;125 Suppl 1:S4-6. _x000D_ 6: Toomey JR, Valocik RE, Koster PF, Gabriel MA, McVey M, Hart TK, Ohlstein EH, Parsons AA, Barone FC. Inhibition of factor IX(a) is protective in a rat model of thromboembolic stroke Stroke. 2002 Feb;33(2):578-85. _x000D_ 7: Shojaei S, Panjehshahin MR, Shafiee SM, Khoshdel Z, Borji M, Ghasempour G, Owji AA. Differential Effects of Resveratrol on the Expression of Brain-Derived Neurotrophic Factor Transcripts and Protein in the Hippocampus of Rat Brain Iran J Med Sci. 2017 Jan;42(1):32-39._x000D_ 8: Willingham AK, Matschiner JT. Functional characterization of single-chain factor X from rat liver Arch Biochem Biophys. 1984 May 1;230(2):543-52. _x000D_ 9: Feuerstein GZ, Toomey JR, Valocik R, Koster P, Patel A, Blackburn MN. An inhibitory anti-factor IX antibody effectively reduces thrombus formation in a rat model of venous thrombosis Thromb Haemost. 1999 Nov;82(5):1443-5._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/10595635">10: Feuerstein GZ, Toomey JR, Valocik R, Koster P, Patel A, Blackburn MN. An inhibitory anti-factor IX antibody effectively reduces thrombus formation in a rat model of venous thrombosis Thromb Haemost. 1999 Nov;82(5):1443-5.</a>_x000D_ <br><strong>Products Related to Rat Factor Ixa can be found at</strong> <a href="https://moleculardepot.com/product-category/Enzymes/"> Enzymes</a>