3-Methyladenine (Highly Pure)

<strong>3-Methyladenine (Highly Pure)</strong>_x000D_ <strong>Catalog number:</strong> B2017833_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 50 mg_x000D_ <strong>Molecular Weight or Concentration:</strong> 149.15 g/mol_x000D_ <strong>Supplied as:</strong> Powder_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> RT_x000D_ <strong>Keywords:</strong> 3-MA, 6-Amino-3-methylpurine_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Yang N, Shang Y. Ferrostatin-1 and 3-Methyladenine Ameliorate Ferroptosis in OVA-Induced Asthma Model and in IL-13-Challenged BEAS-2B Cells Oxid Med Cell Longev. 2022 Feb 4;2022:9657933._x000D_ 2: Dong Y, Wu Y, Zhao GL, Ye ZY, Xing CG, Yang XD. Inhibition of autophagy by 3-MA promotes hypoxia-induced apoptosis in human colorectal cancer cells Eur Rev Med Pharmacol Sci. 2019 Feb;23(3):1047-1054._x000D_ 3: Jung JY, Choi H, Son ED, Kim HJ. 3-Methyladenine Inhibits Procollagen-1 and Fibronectin Expression in Dermal Fibroblasts Independent of Autophagy Curr Mol Med. 2020;20(9):741-750._x000D_ 4: Zhang X, Zhang L, Bi Y, Xi T, Zhang Z, Huang Y, Lu YY, Liu X, Shu S, Fang F. Inhibition of autophagy by 3-methyladenine restricts murine cytomegalovirus replication J Med Virol. 2021 Aug;93(8):5001-5016._x000D_ 5: Wu ST, Han SS, Xu XM, Sun HJ, Zhou H, Shang K, Liu ZH, Liang SJ. 3-Methyladenine ameliorates surgery-induced anxiety-like behaviors in aged mice by inhibiting autophagy-induced excessive oxidative stress Metab Brain Dis. 2023 Aug;38(6):1913-1923._x000D_ 6: Zhao F, Feng G, Zhu J, Su Z, Guo R, Liu J, Zhang H, Zhai Y. 3-Methyladenine-enhanced susceptibility to sorafenib in hepatocellular carcinoma cells by inhibiting autophagy Anticancer Drugs. 2021 Apr 1;32(4):386-393._x000D_ 7: Kosic M, Paunovic V, Ristic B, Mircic A, Bosnjak M, Stevanovic D, Kravic-Stevovic T, Trajkovic V, Harhaji-Trajkovic L. 3-Methyladenine prevents energy stress-induced necrotic death of melanoma cells through autophagy-independent mechanisms J Pharmacol Sci. 2021 Sep;147(1):156-167._x000D_ 8: Bo Q, Shen M, Xiao M, Liang J, Zhai Y, Zhu H, Jiang M, Wang F, Luo X, Sun X. 3-Methyladenine Alleviates Experimental Subretinal Fibrosis by Inhibiting Macrophages and M2 Polarization Through the PI3K/Akt Pathway J Ocul Pharmacol Ther. 2020 Oct;36(8):618-628._x000D_ 9: Wear D, Bhagirath E, Balachandar A, Vegh C, Pandey S. Autophagy Inhibition via Hydroxychloroquine or 3-Methyladenine Enhances Chemotherapy-Induced Apoptosis in Neuro-Blastoma and Glioblastoma Int J Mol Sci. 2023 Jul 27;24(15):12052._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/31916058">10: Wang X, Wu Y. Protective effects of autophagy inhibitor 3-methyladenine on ischemia-reperfusion-induced retinal injury Int Ophthalmol. 2020 May;40(5):1095-1101. </a>_x000D_ _x000D_ <strong>Products Related to 3-Methyladenine (Highly Pure) can be found at</strong> <a href="https://moleculardepot.com/product-category/Chemicals/"> Chemicals</a>