Omiganan (pentahydrochloride)

Omiganan pentahydrochloride is a cationic peptide compound with a broad antibacterial profile. Omiganan pentahydrochloride is capable of inhibiting a variety of bacteria, including yeast, and is active against both gram-positive and gram-negative bacteria. Omiganan pentahydrochloride is able to interact with the bacterial cell membrane, causing the destruction of the cell membrane and the death of the bacteria. Omiganan pentahydrochloride can be used for the study of antimicrobial activity against pathogens commonly associated with catheter-associated infections, including strains with drug-resistant phenotypes[1].

Product Specifications

CAS Number

[269062-93-3]

UNSPSC

12352209

Target

Bacterial

Type

Peptides

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/omiganan-pentahydrochloride.html

Smiles

O=C(N1[C@@H](CCC1)C(N[C@H](C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@H](C(N)=O)CCCCN)=O)=O)=O)CC2=CNC3=CC=CC=C23)=O)[C@@H](NC([C@@H](NC([C@H]4N(CCC4)C([C@@H](NC([C@H](CCCNC(N)=N)NC([C@H](CC(C)C)NC([C@@H](N)[C@@H](C)CC)=O)=O)=O)CC5=CNC6=CC=CC=C56)=O)=O)CC7=CNC8=CC=CC=C78)=O)CC9=CNC%10=CC=CC=C9%10.Cl.Cl.Cl.Cl.Cl

Molecular Formula

C90H132Cl5N27O12

Molecular Weight

1961.45

References & Citations

[1]Fritsche T R, et al. Antimicrobial activity of omiganan pentahydrochloride tested against contemporary bacterial pathogens commonly responsible for catheter-associated infections[J]. Journal of antimicrobial chemotherapy, 2008, 61 (5) : 1092-1098.