AHR-5333 (mandelate)
AHR-5333 mandelate is a selective human blood neutrophil 5-lipoxygenase inhibitor. AHR-5333 mandelate exhibits potent, long-acting activity in rat and guinea pig in vivo models of immediate hypersensitivity[1].
Product Specifications
CAS Number
128766-12-1
UNSPSC
12352005
Target
Lipoxygenase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Endocrinology
Assay Protocol
https://www.medchemexpress.com/ahr-5333-mandelate.html
Smiles
O=C(C(C1=CC=CC=C1)O)O.O=C(C)C2=CC=C(C(OC)=C2)OCCCN3CCC(C(C4=CC=C(C=C4)F)(C5=CC=C(C=C5)F)O)CC3
Molecular Formula
C38H41F2NO7
Molecular Weight
661.73
References & Citations
[1]J M Yanni, et al. Effects of AHR-5333, a new potential antiallergy compound, in in vivo models of immediate hypersensitivity. Int Arch Allergy Appl Immunol. 1988;85 (4) :428-33.|[2]G. Graff, et al. 1-[4-[3-[4-[Bis (4-fluorophenyl) hydroxymethyl]-1-piperidinyl] propoxy]-3]-methoxyphenyl] ethanone (AHR-5333) : A selective human blood neutrophil 5-lipoxygenase inhibitor. Prostaglandins. Volume 38, Issue 4, October 1989, Pages 473-496
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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