RO-76
Product Specifications
UNSPSC Description
RO-76 is a mu opioid receptor (μOR) selective partial agonist. RO-76 binds to μOR-G-protein complex with an EC50 value of 454 nM. RO-76 reduces β-Arrestin-1/2 recruitment. RO-76 shows antinociception activity[1].
Target Antigen
Opioid Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein;Neuronal Signaling
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ro-76.html
Smiles
OCC1=CC=CC(CN(C2CCN(CCC3=CC=CC=C3)CC2)C(CC)=O)=C1
Molecular Weight
380.52
References & Citations
[1]Rohini S. Ople, et al. Signaling Modulation Mediated by Ligand Water Interactions with the Sodium Site at μOR. ACS Cent. Sci. 2024.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-162728/RO-76-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-162728/
Clinical Information
No Development Reported
Curated Selection
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