Anticancer agent 43
Anticancer Agent 43 is a potent anticancer agent. Anticancer Agent 43 induces apoptosis by caspase 3, PARP1, and Bax dependent mechanisms. Anticancer Agent 43 induces DNA damage[1].
Product Specifications
CAS Number
2470015-35-9
UNSPSC
12352005
Hazard Statement
H302-H315-H319
Target
Apoptosis; Bcl-2 Family; Caspase; PARP
Type
Reference compound
Related Pathways
Apoptosis; Cell Cycle/DNA Damage; Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/anticancer-agent-43.html
Purity
98.58
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
COC(C1=C(C2=C(N1)C=CC(F)=C2)/C=C3SC(NC\3=O)=S)=O
Molecular Formula
C14H9FN2O3S2
Molecular Weight
336.36
Precautions
P264-P270-P280-P302+P352-P305+P351+P338-P330-P362+P364-P501
References & Citations
[1]Kryshchyshyn-Dylevych A, et al. Synthesis of novel indole-thiazolidinone hybrid structures as promising scaffold with anticancer potential. Bioorg Med Chem. 2021; 50:116453.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Bax; Caspase 3; PARP1
Available Sizes
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