Anticancer agent 43

Anticancer Agent 43 is a potent anticancer agent. Anticancer Agent 43 induces apoptosis by caspase 3, PARP1, and Bax dependent mechanisms. Anticancer Agent 43 induces DNA damage[1].

Product Specifications

CAS Number

[2470015-35-9]

UNSPSC

12352005

Hazard Statement

H302-H315-H319

Target

Apoptosis; Bcl-2 Family; Caspase; PARP

Type

Reference compound

Related Pathways

Apoptosis; Cell Cycle/DNA Damage; Epigenetics

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/anticancer-agent-43.html

Purity

98.58

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

COC(C1=C(C2=C(N1)C=CC(F)=C2)/C=C3SC(NC\3=O)=S)=O

Molecular Formula

C14H9FN2O3S2

Molecular Weight

336.36

Precautions

P264-P270-P280-P302+P352-P305+P351+P338-P330-P362+P364-P501

References & Citations

[1]Kryshchyshyn-Dylevych A, et al. Synthesis of novel indole-thiazolidinone hybrid structures as promising scaffold with anticancer potential. Bioorg Med Chem. 2021; 50:116453.