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(S, R, S) -AHPC-Ala

(S, R, S) -AHPC-Ala is a ligand for E3 ubiquitinase. (S, R, S) -AHPC-Ala can be used to synthesize PROTAC SMARCA2/4-degrader-23.

Product Specifications

CAS Number

2641319-58-4

UNSPSC

12352005

Target

Ligands for E3 Ligase

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/s-r-s-ahpc-ala.html

Smiles

N[C@H](C(N1[C@H](C(NCC2=CC=C(C=C2)C3=C(C)N=CS3)=O)C[C@@H](OC([C@H](C)N)=O)C1)=O)C(C)(C)C

Molecular Formula

C25H35N5O4S

Molecular Weight

501.64

References & Citations

[1]Preparation of heterocyclic compounds as SMARCA degraders and uses thereof. USA, US20230072658A1 2020-12-17

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

Von Hippel-Lindau (VHL)

Frequently Asked Questions

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