EGFR (Phospho-Tyr1173) Rabbit mAb [KD Validated] Antibody
The epidermal growth factor (EGF) receptor is a transmembrane tyrosine kinase that belongs to the HER/ErbB protein family. Ligand binding results in receptor dimerization, autophosphorylation, activation of downstream signaling, internalization, and lysosomal degradation. The GRB2 adaptor protein binds activated EGFR at phospho-Tyr1068.
Product Specifications
Product Name Alternative
EC 2.7.10.1; ERBB1; Epidermal growth factor receptor precursor; kinase EGFR
UniProt
P00533
Reactivity
Human
Immunogen
A synthesized peptide derived from human Phospho-EGFR (Y1173)
Clonality
Monoclonal
Conjugation
Unconjugated
Source
Recombinant Rabbit
Field of Research
Cell Biology
Purification
Affinity-chromatography
Dilution
WB:1:500~1:2000 IHC:1:50~1:100 ICC/IF:1:50~1:100 IP:1:20
Form
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Molecular Weight
175kDa
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
ICC, IHC, IP, WB
Host or Source
Rabbit
Isotype
Rabbit IgG
Available Sizes
Frequently Asked Questions
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