EGFR (Phospho-Tyr1173) Rabbit mAb [KD Validated] Antibody
The epidermal growth factor (EGF) receptor is a transmembrane tyrosine kinase that belongs to the HER/ErbB protein family. Ligand binding results in receptor dimerization, autophosphorylation, activation of downstream signaling, internalization, and lysosomal degradation. The GRB2 adaptor protein binds activated EGFR at phospho-Tyr1068.
Product Specifications
Product Name Alternative
EC 2.7.10.1; ERBB1; Epidermal growth factor receptor precursor; kinase EGFR
UniProt
P00533
Reactivity
Human
Immunogen
A synthesized peptide derived from human Phospho-EGFR (Y1173)
Clonality
Monoclonal
Conjugation
Unconjugated
Source
Recombinant Rabbit
Field of Research
Cell Biology
Purification
Affinity-chromatography
Dilution
WB:1:500~1:2000 IHC:1:50~1:100 ICC/IF:1:50~1:100 IP:1:20
Form
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Molecular Weight
175kDa
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
ICC, IHC, IP, WB
Host or Source
Rabbit
Isotype
Rabbit IgG
Available Sizes
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
Human Alpha B Crystallin (CRYAB) activation kit by CRISPRa
