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GRP78 BiP Rabbit mAb [KD Validated] Antibody

When Chinese hamster K12 cells are starved of glucose, the synthesis of several proteins, called glucose-regulated proteins (GRPs), is markedly increased. Hendershot et al. (1994) (PubMed 8020977) pointed out that one of these, GRP78 (HSPA5), also referred to as 'immunoglobulin heavy chain-binding protein' (BiP), is a member of the heat-shock protein-70 (HSP70) family and is involved in the folding and assembly of proteins in the endoplasmic reticulum (ER) .

Product Specifications

Product Name Alternative

GRP-78; GRP78; BIP; MIF2; HSPA5

UniProt

P11021

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human GRP78 BiP

Clonality

Monoclonal

Conjugation

Unconjugated

Source

Recombinant Rabbit

Field of Research

Cell Biology

Purification

Affinity-chromatography

Dilution

WB:1:500~1:2000IHC:1:50~1:200

Form

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Molecular Weight

78kDa

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Notes

For research use only.

Tested Applications

IHC, WB

Host or Source

Rabbit

Isotype

Rabbit IgG

Available Sizes

Frequently Asked Questions

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