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Caspase-2 Rabbit mAb [KD Validated] Antibody

Caspase-2 (Nedd2, ICH-1) is an aspartate-specific cysteine protease that is activated in response to various apoptotic stimuli. Caspase-2 is unique among the caspases in that it has features of both upstream caspases (long prodomain) and downstream caspases (DEXD substrate specificity) . Caspase-2 is highly expressed in the brain during development and is expressed at low levels in adult tissue.

Product Specifications

Product Name Alternative

Caspase-2; Caspase 2; Caspase2; CASP-2; Neural precursor cell expressed developmentally down-regulated protein 2; NEDD-2; Protease ICH-1; CASP2; ICH1; NEDD2

UniProt

P42575

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human Caspase-2

Clonality

Monoclonal

Conjugation

Unconjugated

Source

Recombinant Rabbit

Field of Research

Cell Biology

Purification

Affinity-chromatography

Dilution

WB:1:500~2000IHC:50~200ICC/IF:50~200

Form

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Molecular Weight

48,30,12kDa

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Notes

For research use only.

Tested Applications

FC, ICC, IHC, WB

Host or Source

Rabbit

Isotype

Rabbit IgG

Available Sizes

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