Keratinocyte Growth Factor 1/FGF-7 (Human)

<strong>Keratinocyte Growth Factor 1/FGF-7 (Human)</strong>_x000D_ <strong>Catalog number:</strong> B2010315_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Volume/Weight:</strong> 10 ug_x000D_ <strong>pH:</strong> 7.4 upon reconstitution_x000D_ <strong>Supplied as:</strong> Lyophilized Powder_x000D_ <strong>Appearance:</strong> Powder_x000D_ <strong>Applications:</strong> highly pure Keratinocyte Growth Factor 1/FGF-7 (Human) expressed in CHO. This protein acts as a mitogen peptide from the fibroblast growth factors family. This factor binds only to a splice variant of FGFR2 (FGFR2 IIIb) and is a highly specific paracrine growth factor for epithelial cells._x000D_ <strong>Storage:</strong> -20C_x000D_ <strong>Keywords:</strong> rHuKGF-1/FGF-7; Keratinocyte Growth Factor; Fibroblast Growth Factor-7; HBGF-7_x000D_ <strong>Grade:</strong> Biotechnology grade. All components are highly pure (minimum 95%). All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Nguyen D, Sulaiman OAR. Transforming Growth Factor Beta 1 Regulates_x000D_ Fibroblast Growth Factor 7 Expression in Schwann Cells. Ochsner J. 2019_x000D_ Spring;19(1):7-12._x000D_ _x000D_ 2: Lee CY, Yang CY, Lin CC, Yu MC, Sheu SJ, Kuan YH. Hair growth is promoted by_x000D_ BeauTop via expression of EGF and FGF‑7. Mol Med Rep. 2018 Jun;17(6):8047-8052._x000D_ _x000D_ 3: Tsuboi R, Sato C, Kurita Y, Ron D, Rubin JS, Ogawa H. Keratinocyte growth_x000D_ factor (FGF-7) stimulates migration and plasminogen activator activity of normal_x000D_ human keratinocytes. J Invest Dermatol. 1993 Jul;101(1):49-53._x000D_ _x000D_ 4: Trowbridge JM, Rudisill JA, Ron D, Gallo RL. Dermatan sulfate binds and_x000D_ potentiates activity of keratinocyte growth factor (FGF-7). J Biol Chem. 2002_x000D_ Nov 8;277(45):42815-20._x000D_ _x000D_ 5: Lyakhovich A, Aksenov N, Pennanen P, Miettinen S, Ahonen MH, Syvälä H,_x000D_ Ylikomi T, Tuohimaa P. Vitamin D induced up-regulation of keratinocyte growth_x000D_ factor (FGF-7/KGF) in MCF-7 human breast cancer cells. Biochem Biophys Res_x000D_ Commun. 2000 Jul 5;273(2):675-80._x000D_ _x000D_ 6: Zhang T, Guan H, Yang K. Keratinocyte growth factor promotes preadipocyte_x000D_ proliferation via an autocrine mechanism. J Cell Biochem. 2010 Mar_x000D_ 1;109(4):737-46._x000D_ _x000D_ 7: Kovacs D, Falchi M, Cardinali G, Raffa S, Carducci M, Cota C, Amantea A,_x000D_ Torrisi MR, Picardo M. Immunohistochemical analysis of keratinocyte growth_x000D_ factor and fibroblast growth factor 10 expression in psoriasis. Exp Dermatol._x000D_ 2005 Feb;14(2):130-7._x000D_ _x000D_ 8: Mason IJ, Fuller-Pace F, Smith R, Dickson C. FGF-7 (keratinocyte growth_x000D_ factor) expression during mouse development suggests roles in myogenesis,_x000D_ forebrain regionalisation and epithelial-mesenchymal interactions. Mech Dev._x000D_ 1994 Jan;45(1):15-30._x000D_ _x000D_ 9: Strain AJ, McGuinness G, Rubin JS, Aaronson SA. Keratinocyte growth factor_x000D_ and fibroblast growth factor action on DNA synthesis in rat and human_x000D_ hepatocytes: modulation by heparin. Exp Cell Res. 1994 Feb;210(2):253-9._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/15976484/">10: Wollenhaupt K, Welter H, Brüssow KP, Einspanier R. Regulation of endometrial_x000D_ fibroblast growth factor 7 (FGF-7) and its receptor FGFR2IIIb in gilts after sex_x000D_ steroid replacements, and during the estrous cycle and early gestation. J Reprod_x000D_ Dev. 2005 Aug;51(4):509-19. </a>_x000D_ _x000D_ <strong>Products Related to Keratinocyte Growth Factor 1/FGF-7 (Human) </strong> <a href="https://moleculardepot.com/product-category/Proteins/">: Proteins</a>