KKII5
Product Specifications
UNSPSC Description
KKII5 is a potent Lipoxygenase (LOX-1) inhibitor with an IC50 of 19 μM. KKII5 inhibits lipid peroxidation[1].
Target Antigen
Lipoxygenase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/kkii5.html
Purity
98.60
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
C1=CC=C(C=C1)C2C=C(NC(=S)N2)C3=CC=CC=C3
Molecular Weight
266.36
References & Citations
[1]Georgiou N, et al. Thiocarbohydrazone and Chalcone-Derived 3,4-Dihydropyrimidinethione as Lipid Peroxidation and Soybean Lipoxygenase Inhibitors. ACS Omega. 2023 Mar 21;8(13):11966-11977.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-W488004/KKII5-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-W488004/KKII5-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
6381-55-1
Available Sizes
Curated Selection
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