COPS3 Rabbit mAb [KD Validated] Antibody
Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2.
Product Specifications
Product Name Alternative
COP9 subunit 3; cops3; CSN3; JAB 1 containing signalosome subunit 3; SGN3; Signalosome subunit 3
UniProt
Q9UNS2
Reactivity
Human, Mouse, Rat
Immunogen
A synthesized peptide derived from human COPS3
Clonality
Monoclonal
Conjugation
Unconjugated
Source
Recombinant Rabbit
Purification
Affinity-chromatography
Dilution
WB:1:500~1:2000ICC/IF:1:50~1:200IP:1:50FC:1:50
Form
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Molecular Weight
48 kDa
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
FC, ICC, IP, WB
Host or Source
Rabbit
Isotype
Rabbit IgG
Available Sizes
Frequently Asked Questions
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