CRKII Rabbit mAb [KD Validated] Antibody
The Crk-I and Crk-II forms differ in their biological activities. Crk-II has less transforming activity than Crk-I. Crk-II mediates attachment-induced MAPK8 activation, membrane ruffling and cell motility in a Rac-dependent manner. Involved in phagocytosis of apoptotic cells and cell motility via its interaction with DOCK1 and DOCK4.
Product Specifications
Product Name Alternative
CRK; CRKII; p38
UniProt
P46108
Reactivity
Human, Mouse, Rat
Immunogen
A synthesized peptide derived from human CRKII
Clonality
Monoclonal
Conjugation
Unconjugated
Source
Recombinant Rabbit
Purification
Affinity-chromatography
Dilution
WB:1:500~1:2000ICC/IF:1:50~1:200IP:1:50FC:1:100
Form
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Molecular Weight
38kDa
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
FC, ICC, IP, WB
Host or Source
Rabbit
Isotype
Rabbit IgG
Available Sizes
Frequently Asked Questions
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