What is the catalog number for Benzyl isothiocyanate?

The catalog number for Benzyl isothiocyanate is HY-77813.

What sizes are available for Benzyl isothiocyanate?

Benzyl isothiocyanate is available in the following size(s): 100 mg, 10 mM - 1 mL.

How many pack sizes does Benzyl isothiocyanate come in?

Benzyl isothiocyanate is available in 2 different pack sizes.

Is Benzyl isothiocyanate in stock?

Benzyl isothiocyanate is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Benzyl isothiocyanate?

Benzyl isothiocyanate is manufactured by QuantiMol.

What is the estimated delivery time for Benzyl isothiocyanate?

Estimated delivery time for Benzyl isothiocyanate is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Benzyl isothiocyanate?

The safety data sheet for Benzyl isothiocyanate is available here: http://file.medchemexpress.com/batch_PDF/HY-77813/Benzyl-isothiocyanate-SDS-MedChemExpress.pdf.

Benzyl isothiocyanate

Benzyl isothiocyanate is an orally available isothiocyanate with bactericidal, anticancer, antiangiogenic and anthelmintic activities. Benzyl isothiocyanate exerts anticancer functions by regulating multiple signaling pathways, including apoptosis, cell proliferation, cell cycle arrest, metastasis, angiogenesis, and autophagy. In addition, Benzyl isothiocyanate can enhance muscle insulin sensitivity to improve obesity-induced hyperglycemia[1][2][3][4][5][6][7][8][9].

Product Specifications

CAS Number

622-78-6

UNSPSC

12352005

Hazard Statement

H302, H315, H317, H319, H334, H335

Target

Antibiotic; Apoptosis; Autophagy; Bacterial; Parasite; Reactive Oxygen Species (ROS)

Type

Natural Products

Related Pathways

Anti-infection; Apoptosis; Autophagy; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

Applications

Neuroscience-Neurodegeneration

Field of Research

Cancer; Infection; Endocrinology

Assay Protocol

https://www.medchemexpress.com/benzyl-isothiocyanate.html

Concentration

10mM

Purity

99.62

Solubility

DMSO : 100 mg/mL (ultrasonic) |H2O : < 0.1 mg/mL

Smiles

S=C=NCC1=CC=CC=C1

Molecular Formula

C8H7NS

Molecular Weight

149.21

Precautions

H302, H315, H317, H319, H334, H335

References & Citations

[1]Abdel-Kader MS, et al. Quantitative Analysis of Benzyl Isothiocyanate in Salvadora persica Extract and Dental Care Herbal Formulations Using Reversed Phase C18 High-Performance Liquid Chromatography Method. Pharmacogn Mag. 2017 Oct;13 (Suppl 3) :S412-S416.|[2]Lai KC, et al. Benzyl isothiocyanate and phenethyl isothiocyanate inhibit murine melanoma B16F10 cell migration and invasion in vitro. Int J Oncol. 2017 Sep;51 (3) :832-840.|[3]Dinh T N, et al. Anticancer activities of dietary benzyl isothiocyanate: A comprehensive review[J]. Pharmacological Research, 2021, 169: 105666.|[4]Kassie F, et al. Genotoxic effects of benzyl isothiocyanate, a natural chemopreventive agent[J]. Mutagenesis, 1999, 14 (6) : 595-604.|[5]Kermanshai R, et al. Benzyl isothiocyanate is the chief or sole anthelmintic in papaya seed extracts[J]. Phytochemistry, 2001, 57 (3) : 427-435.|[6]Jensen J, et al. The toxic effects of benzyl glucosinolate and its hydrolysis product, the biofumigant benzyl isothiocyanate, to Folsomia fimetaria[J]. Environmental Toxicology and Chemistry, 2010, 29 (2) : 359-364.|[7]Pintão A M, et al. In vitro and in vivo antitumor activity of benzyl isothiocyanate: a natural product from Tropaeolum majus[J]. Planta Medica, 1995, 61 (03) : 233-236.|[8]Chuang W T, et al. Benzyl isothiocyanate ameliorates high-fat diet-induced hyperglycemia by enhancing Nrf2-dependent antioxidant defense-mediated IRS-1/AKT/TBC1D1 signaling and GLUT4 expression in skeletal muscle[J]. Journal of agricultural and food chemistry, 2020, 68 (51) : 15228-15238.|[9]Dinh T N, et al. Anticancer activities of dietary benzyl isothiocyanate: A comprehensive review[J]. Pharmacological Research, 2021, 169: 105666.