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Nav1.8-IN-4

Nav1.8-IN-4 (compound 9a) is a Nav1.8 channel inhibitor (IC50=0.014 μM) . Nav1.8-IN-4 can be used for research on pain-related diseases[1].

Product Specifications

CAS Number

1620846-16-3

UNSPSC

12352005

Hazard Statement

H315, H319, H320

Target

Sodium Channel

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/nav1-8-in-4.html

Purity

99.78

Solubility

DMSO : 116.67 mg/mL (ultrasonic)

Smiles

O=C1C=C(NC(C2=CC=C(C(F)(F)F)C=C2OC3=CC=C(C=C3C)F)=O)C=CN1

Molecular Formula

C20H14F4N2O3

Molecular Weight

406.33

Precautions

H315, H319, H320

References & Citations

[1]Corey Anderson, et al. Prodrugs of pyridone amides useful as modulators of sodium channels. Patent WO2015089361A1.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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