Nav1.8-IN-4
Nav1.8-IN-4 (compound 9a) is a Nav1.8 channel inhibitor (IC50=0.014 μM) . Nav1.8-IN-4 can be used for research on pain-related diseases[1].
Product Specifications
CAS Number
1620846-16-3
UNSPSC
12352005
Hazard Statement
H315, H319, H320
Target
Sodium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/nav1-8-in-4.html
Purity
99.78
Solubility
DMSO : 116.67 mg/mL (ultrasonic)
Smiles
O=C1C=C(NC(C2=CC=C(C(F)(F)F)C=C2OC3=CC=C(C=C3C)F)=O)C=CN1
Molecular Formula
C20H14F4N2O3
Molecular Weight
406.33
Precautions
H315, H319, H320
References & Citations
[1]Corey Anderson, et al. Prodrugs of pyridone amides useful as modulators of sodium channels. Patent WO2015089361A1.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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