Nav1.8-IN-4
Nav1.8-IN-4 (compound 9a) is a Nav1.8 channel inhibitor (IC50=0.014 μM) . Nav1.8-IN-4 can be used for research on pain-related diseases[1].
Product Specifications
CAS Number
[1620846-16-3]
UNSPSC
12352005
Hazard Statement
H315, H319, H320
Target
Sodium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/nav1-8-in-4.html
Purity
99.78
Solubility
DMSO : 116.67 mg/mL (ultrasonic)
Smiles
O=C1C=C(NC(C2=CC=C(C(F)(F)F)C=C2OC3=CC=C(C=C3C)F)=O)C=CN1
Molecular Formula
C20H14F4N2O3
Molecular Weight
406.33
Precautions
H315, H319, H320
References & Citations
[1]Corey Anderson, et al. Prodrugs of pyridone amides useful as modulators of sodium channels. Patent WO2015089361A1.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
38764124 3x 1.0µg DNA
RDH10 CRISPRa sgRNA lentivector (set of three targets)(Mouse)
Ask
View Details 
K0090-02-HRP 100 µL
Kappa Light Chain (HCAK1, Ig kappa Chain C Region, IGKC, Immunoglobulin kappa Constant Region, Immunoglobulin kappa Light Chain, Kappa 1 Immunoglobulin Light Chain, Km, MGC111575, MGC62011, MGC72072, MGC88770, MGC88771, MGC88809) (HRP) discontinued
Ask
View Details 
GTR15108944 1 Vial
Lentiviral human KMO shRNA (UAS) - Lentiviral human KMO shRNA (UAS, GFP) (25)
Ask
View Details GTR15131850 1 Vial
Lentiviral human QRFPR shRNA (UAS) - Lentiviral human QRFPR shRNA (UAS) (100)
Ask
View Details 362293 200 µL
BMP15 (Bone Morphogenetic Protein 15, GDF9B, GDF9-B, ODG2, POF4, Growth/differentiation Factor 9B)
Ask
View Details