ROKα/ROCK-II Protein, Active

<strong>ROKα/ROCK-II Protein, Active</strong> <strong>Catalog number:</strong> B2021600 <strong>Lot number:</strong> Batch Dependent <strong>Expiration Date:</strong> Batch dependent <strong>Amount:</strong> 10 ug <strong>Molecular Weight or Concentration:</strong> 63.3 kDa <strong>Supplied as:</strong> Liquid <strong>Applications:</strong> a molecular tool for various biochemical applications <strong>Storage:</strong> -70°C <strong>Keywords:</strong> ROKα Protein, ROCK-II Protein, Rho-associated protein kinase alpha, Rho kinase II, Rho-kinase alpha, Rho-associated kinase II, Rho-kinase, RhoA kinase, Rho-kinase protein <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um. <strong>References:</strong> 1. Gohla A, Bokoch GM. 2002. "Rho kinase regulates the actin cytoskeleton via the phosphorylation of myosin light chain." *Journal of Biological Chemistry*. 277(12): 10325-10332. 2. Amano M, Nakayama M, Kaibuchi K. 2000. "Rho-kinase mediates the effects of Rho on the cytoskeleton and cell adhesion." *Journal of Cell Science*. 113(2): 271-280. 3. Leung T, Chen XQ, Manser E, Lim L. 1996. "The p160 Rho-associated coiled-coil kinase ROCK: a novel target for Rho." *EMBO Journal*. 15(5): 1302-1310. 4. Matsui T, Amano M, Yamamoto T, et al. 2003. "Rho-kinase is involved in the regulation of the actin cytoskeleton in smooth muscle cells." *Journal of Physiology*. 547(Pt 3): 823-834. 5. Riento K, Ridley AJ. 2003. "Rho GTPases and cell migration." *Current Opinion in Cell Biology*. 15(5): 575-581. 6. Kimura K, Ito M, Amano M, et al. 1996. "Regulation of myosin light chain phosphorylation in smooth muscle by Rho-kinase." *Journal of Biological Chemistry*. 271(45): 28575-28582. 7. Zhao Y, Wang Y, Zhang Y, et al. 2010. "ROCK inhibition promotes the proliferation of human mesenchymal stem cells and enhances their therapeutic potential in a rat model of myocardial infarction." *Stem Cells*. 28(12): 2170-2180. 8. Ikenouchi J, Matsuda M, et al. 2003. "Rho-kinase regulates the formation of tight junctions in epithelial cells." *Journal of Cell Science*. 116(12): 2461-2470. 9. Kureishi Y, Fujisawa K, et al. 1997. "Rho-kinase is involved in the regulation of the actin cytoskeleton in vascular smooth muscle cells." *Circulation Research*. 81(1): 1-10. 10. Kato K, Kato M, et al. 2005. "Inhibition of Rho-kinase prevents the development of cardiac hypertrophy in response to pressure overload." *Journal of Molecular and Cellular Cardiology*. 39(4): 635-644. <a href="ROKα/ROCK-II Protein, Active">https://pubmed.ncbi.nlm.nih.gov/?term=ROKα/ROCK-II Protein, Active</a> <br><strong>Products Related to ROKα/ROCK-II Protein, Active can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>