Dichlorphenamide

Dichlorphenamide (Diclofenamide) is an orally active, specific, carbonic anhydrase inhibitor. Dichlorphenamide can reduce intraocular pressure by inhibiting the secretion of water from the eye. Dichlorphenamide can be used for glaucoma research[1].

Product Specifications

CAS Number

[120-97-8]

Product Name Alternative

Diclofenamide

UNSPSC

12352005

Hazard Statement

H302, H361

Target

Carbonic Anhydrase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/Dichlorphenamide.html

Purity

98.49

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=S(C1=CC(Cl)=C(Cl)C(S(=O)(N)=O)=C1)(N)=O

Molecular Formula

C6H6Cl2N2O4S2

Molecular Weight

305.16

Precautions

H302, H361

References & Citations

[1]Kanski, J.J., Carbonic anhydrase inhibitors and osmotic agents in glaucoma. Carbonic anhydrase inhibitors. Br J Ophthalmol, 1968. 52 (8) : p. 642-3.|[2]Rucquoy, M. and L. Sorel, Diclofenamide in the treatment of therapy-resistant epilepsy. Acta Neurol Belg, 1978. 78 (3) : p. 174-82.