BS3 Crosslinker
BS3 Crosslinker is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1].
Product Specifications
CAS Number
[82436-77-9]
UNSPSC
12352203
Hazard Statement
H302, H315, H319, H335
Target
ADC Linker
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/bs3-crosslinker.html
Purity
99.84
Solubility
DMSO : 175 mg/mL (ultrasonic) |H2O : 100 mg/mL (ultrasonic)
Smiles
O=C(CCCCCCC(ON1C(C(CC1=O)S(=O)(O)=O)=O)=O)ON2C(C(CC2=O)S(=O)(O)=O)=O
Molecular Formula
C16H20N2O14S2
Molecular Weight
528.47
Precautions
H302, H315, H319, H335
References & Citations
[1]Kotite N J, et al. Interaction of specific platelet membrane proteins with collagen: evidence from chemical crosslinking[J]. Biochemistry, 1984, 23 (13) : 3099-3104.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
Non-cleavable Linker
Available Sizes
Curated Selection
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