Resorufin benzyl ether
Resorufin benzyl ether (BzRes), a fluorogenic enzyme substrate, can be used to detect CYP3A4 enzyme activity. Resorufin benzyl ether modified with a recognizing moiety boronate, can be used for ONOO- detection via a self-immolation mechanism. Ex/Em=530-570 nm/590 nm[1][2][3].
Product Specifications
CAS Number
87687-02-3
Product Name Alternative
BzRes; 7-Benzyloxyresorufin; 7-Benzyloxyphenoxazone
UNSPSC
12171500
Hazard Statement
H315-H319-H335
Target
Fluorescent Dye
Type
Dye Reagents
Related Pathways
Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/resorufin-benzyl-ether.html
Solubility
10 mM in DMSO
Smiles
O=C1C=CC2=NC3=C(C=C(OCC4=CC=CC=C4)C=C3)OC2=C1
Molecular Formula
C19H13NO3
Molecular Weight
303.31
Precautions
P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501
References & Citations
[1]Ji X, et al. Regulating the activity of boronate moiety to construct fluorescent probes for the detection of ONOO-in vitro and in vivo. Anal Methods. 2022 Dec 15;14 (48) :5027-5033. |[2]Nuchtavorn N, et al. Paper-based sol-gel thin films immobilized cytochrome P450 for enzyme activity measurement. Anal Chim Acta. 2020 Feb 15;1098:86-93. |[3]Yale SH, et al. Analysis of the inhibitory potential of Ginkgo biloba, Echinacea purpurea, and Serenoa repens on the metabolic activity of cytochrome P450 3A4, 2D6, and 2C9. J Altern Complement Med. 2005 Jun;11 (3) :433-9.
Shipping Conditions
Room temperature
Scientific Category
Dye Reagents
Clinical Information
No Development Reported
Available Sizes
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