Resorufin benzyl ether

Resorufin benzyl ether (BzRes), a fluorogenic enzyme substrate, can be used to detect CYP3A4 enzyme activity. Resorufin benzyl ether modified with a recognizing moiety boronate, can be used for ONOO- detection via a self-immolation mechanism. Ex/Em=530-570 nm/590 nm[1][2][3].

Product Specifications

CAS Number

[87687-02-3]

Product Name Alternative

BzRes; 7-Benzyloxyresorufin; 7-Benzyloxyphenoxazone

UNSPSC

12171500

Hazard Statement

H315-H319-H335

Target

Fluorescent Dye

Type

Dye Reagents

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/resorufin-benzyl-ether.html

Solubility

10 mM in DMSO

Smiles

O=C1C=CC2=NC3=C(C=C(OCC4=CC=CC=C4)C=C3)OC2=C1

Molecular Formula

C19H13NO3

Molecular Weight

303.31

Precautions

P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

References & Citations

[1]Ji X, et al. Regulating the activity of boronate moiety to construct fluorescent probes for the detection of ONOO-in vitro and in vivo. Anal Methods. 2022 Dec 15;14 (48) :5027-5033. |[2]Nuchtavorn N, et al. Paper-based sol-gel thin films immobilized cytochrome P450 for enzyme activity measurement. Anal Chim Acta. 2020 Feb 15;1098:86-93. |[3]Yale SH, et al. Analysis of the inhibitory potential of Ginkgo biloba, Echinacea purpurea, and Serenoa repens on the metabolic activity of cytochrome P450 3A4, 2D6, and 2C9. J Altern Complement Med. 2005 Jun;11 (3) :433-9.