CDG (2-Deoxy-2- (2-oxo-2H-chromen-7-yl) Amino-D-Glucose)

<strong>CDG (2-Deoxy-2-(2-oxo-2H-chromen-7-yl)Amino-D-Glucose)</strong>_x000D_ <strong>Catalog number:</strong> MDP0883_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 0.5 mg_x000D_ <strong>Molecular Weight or Concentration:</strong> 323.3 g/mol_x000D_ <strong>Supplied as:</strong> Powder_x000D_ <strong>Applications:</strong> molecular probe in the monitoring of cellular glucose uptake_x000D_ <strong>Storage:</strong> -20°C_x000D_ <strong>Keywords:</strong> 2-Deoxy-2-(2-oxo-2H-chromen-7-yl)Amino-D-Glucose_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ <strong>Indication for Use:</strong>This product is for Research Use Only. This product is NOT for human or animal use._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Lam C, Krasnewich DM. PMM2-CDG. 2005 Aug 15 [updated 2021 May 20]. In: Adam_x000D_ MP, Ardinger HH, Pagon RA, Wallace SE, Bean LJH, Mirzaa G, Amemiya A, editors._x000D_ GeneReviews^® [Internet]. Seattle (WA): University of Washington,_x000D_ Seattle; 1993–2021._x000D_ _x000D_ 2: Radenkovic S, Bird MJ, Emmerzaal TL, Wong SY, Felgueira C, Stiers KM, Sabbagh_x000D_ L, Himmelreich N, Poschet G, Windmolders P, Verheijen J, Witters P, Altassan R,_x000D_ Honzik T, Eminoglu TF, James PM, Edmondson AC, Hertecant J, Kozicz T, Thiel C,_x000D_ Vermeersch P, Cassiman D, Beamer L, Morava E, Ghesquière B. The Metabolic Map_x000D_ into the Pathomechanism and Treatment of PGM1-CDG. Am J Hum Genet. 2019 May_x000D_ 2;104(5):835-846._x000D_ _x000D_ 3: Monticelli M, Liguori L, Allocca M, Andreotti G, Cubellis MV._x000D_ β-Glucose-1,6-Bisphosphate Stabilizes Pathological Phophomannomutase2 Mutants In_x000D_ Vitro and Represents a Lead Compound to Develop Pharmacological Chaperones for_x000D_ the Most Common Disorder of Glycosylation, PMM2-CDG. Int J Mol Sci. 2019 Aug_x000D_ 26;20(17):4164._x000D_ _x000D_ 4: Schrapers E, Tegtmeyer LC, Simic-Schleicher G, Debus V, Reunert J, Balbach S,_x000D_ Klingel K, Du Chesne I, Seelhöfer A, Fobker M, Marquardt T, Rust S. News on_x000D_ Clinical Details and Treatment in PGM1-CDG. JIMD Rep. 2016;26:77-84._x000D_ _x000D_ 5: Morava E. Galactose supplementation in phosphoglucomutase-1 deficiency;_x000D_ review and outlook for a novel treatable CDG. Mol Genet Metab. 2014_x000D_ Aug;112(4):275-9._x000D_ _x000D_ 6: Marquardt T, Bzduch V, Hogrebe M, Rust S, Reunert J, Grüneberg M, Park J,_x000D_ Callewaert N, Lachmann R, Wada Y, Engel T. SLC37A4-CDG: Mislocalization of the_x000D_ glucose-6-phosphate transporter to the Golgi causes a new congenital disorder of_x000D_ glycosylation. Mol Genet Metab Rep. 2020 Aug 21;25:100636._x000D_ _x000D_ 7: Gao N, Shang J, Lehrman MA. Analysis of glycosylation in CDG-Ia fibroblasts_x000D_ by fluorophore-assisted carbohydrate electrophoresis: implications for_x000D_ extracellular glucose and intracellular mannose 6-phosphate. J Biol Chem. 2005_x000D_ May 6;280(18):17901-9._x000D_ _x000D_ 8: He MF, Fu HQ, Su BF, Yang HQ, Tang JQ, Hu CW. Theoretical insight into the_x000D_ coordination of cyclic β-D-glucose to [Al(OH)(aq)](2+) and [Al(OH)2(aq)](1+)_x000D_ ions. J Phys Chem B. 2014 Dec 4;118(48):13890-902._x000D_ _x000D_ 9: Radenkovic S, Witters P, Morava E. Central nervous involvement is common in_x000D_ PGM1-CDG. Mol Genet Metab. 2018 Nov;125(3):200-204._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/31636082/">10: Iyer S, Sam FS, DiPrimio N, Preston G, Verheijen J, Murthy K, Parton Z,_x000D_ Tsang H, Lao J, Morava E, Perlstein EO. Repurposing the aldose reductase_x000D_ inhibitor and diabetic neuropathy drug epalrestat for the congenital disorder of_x000D_ glycosylation PMM2-CDG. Dis Model Mech. 2019 Nov 11;12(11):dmm040584. </a>_x000D_ _x000D_ <strong>Products Related to CDG (2-Deoxy-2-(2-oxo-2H-chromen-7-yl)Amino-D-Glucose)</strong> <a href="https://moleculardepot.com/product-category/Carbohydrates/">: Carbohydrates</a>