Glycoursodeoxycholic Acid

<strong>Glycoursodeoxycholic Acid</strong>_x000D_ <strong>Catalog number:</strong> B2017522_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 100 mg_x000D_ <strong>Molecular Weight or Concentration:</strong> 449.6_x000D_ <strong>Supplied as:</strong> Powder_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20°C_x000D_ <strong>Keywords:</strong> GUDCA, Ursodeoxycholyl Glycine_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Chen B, Bai Y, Tong F, Yan J, Zhang R, Zhong Y, Tan H, Ma X. Glycoursodeoxycholic acid regulates bile acids level and alters gut microbiota and glycolipid metabolism to attenuate diabetes Gut Microbes. 2023 Jan-Dec;15(1):2192155._x000D_ 2: Cheng L, Chen T, Guo M, Liu P, Qiao X, Wei Y, She J, Li B, Xi W, Zhou J, Yuan Z, Wu Y, Liu J. Glycoursodeoxycholic acid ameliorates diet-induced metabolic disorders with inhibiting endoplasmic reticulum stress Clin Sci (Lond). 2021 Jul 30;135(14):1689-1706._x000D_ 3: Yang W, Feng R, Peng G, Wang Z, Cen M, Jing Y, Feng W, Long T, Liu Y, Li Z, Huang K, Chang G. Glycoursodeoxycholic Acid Alleviates Arterial Thrombosis via Suppressing Diacylglycerol Kinases Activity in Platelet Arterioscler Thromb Vasc Biol. 2024 Jun;44(6):1283-1301._x000D_ 4: Huang K, Liu C, Peng M, Su Q, Liu R, Guo Z, Chen S, Li Z, Chang G. Glycoursodeoxycholic Acid Ameliorates Atherosclerosis and Alters Gut Microbiota in Apolipoprotein E-Deficient Mice J Am Heart Assoc. 2021 Apr 6;10(7):e019820._x000D_ 5: Collins SL, Patterson AD. The gut microbiome: an orchestrator of xenobiotic metabolism Acta Pharm Sin B. 2020 Jan;10(1):19-32._x000D_ 6: Sun L, Xie C, Wang G, Wu Y, Wu Q, Wang X, Liu J, Deng Y, Xia J, Chen B, Zhang S, Yun C, Lian G, Zhang X, Zhang H, Bisson WH, Shi J, Gao X, Ge P, Liu C, Krausz KW, Nichols RG, Cai J, Rimal B, Patterson AD, Wang X, Gonzalez FJ, Jiang C. Gut microbiota and intestinal FXR mediate the clinical benefits of metformin Nat Med. 2018 Dec;24(12):1919-1929._x000D_ 7: Wu Q, Sun L, Hu X, Wang X, Xu F, Chen B, Liang X, Xia J, Wang P, Aibara D, Zhang S, Zeng G, Yun C, Yan Y, Zhu Y, Bustin M, Zhang S, Gonzalez FJ, Jiang C. Suppressing the intestinal farnesoid X receptor/sphingomyelin phosphodiesterase 3 axis decreases atherosclerosis J Clin Invest. 2021 May 3;131(9):e142865._x000D_ 8: Cheng P, Wu J, Zong G, Wang F, Deng R, Tao R, Qian C, Shan Y, Wang A, Zhao Y, Wei Z, Lu Y. Capsaicin shapes gut microbiota and pre-metastatic niche to facilitate cancer metastasis to liver Pharmacol Res. 2023 Feb;188:106643._x000D_ 9: Vaz AR, Cunha C, Gomes C, Schmucki N, Barbosa M, Brites D. Glycoursodeoxycholic acid reduces matrix metalloproteinase-9 and caspase-9 activation in a cellular model of superoxide dismutase-1 neurodegeneration Mol Neurobiol. 2015;51(3):864-77._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/19549210">10: Goldman A, Condon A, Adler E, Minnella M, Bernstein C, Bernstein H, Dvorak K. Protective effects of glycoursodeoxycholic acid in Barrett's esophagus cells Dis Esophagus. 2010 Feb;23(2):83-93. </a>_x000D_ _x000D_ <strong>Products Related to Glycoursodeoxycholic Acid can be found at</strong> <a href="https://moleculardepot.com/product-category/Chemicals/"> Chemicals</a>