AF/LE Purified Anti-Human CD200 Antibody[OX-104]

Product Specifications

Background

CD200 (OX2) and CD200R (OX2R) are membrane glycoprotein members of the Ig superfamily. CD200 is expressed by a range of cells, including neurons, epithelial cells, endothelial cells, fibroblasts, and lymphoid cells, while its receptor, CD200R, is found on myeloid and T cells. Interaction between CD200 and CD200R downregulates macrophage function and plays a role in immunosuppression and regulation of anti-tumor immune responses.

Abbreviation

CD200

Gene ID

4345

UniProt

P41217

Host

Mouse

Reactivity

Human

Immunogen

Recombinant Human CD200 protein

Target

CD 200; OX-2 Membrane Glycoprotein; MOX1; MOX2; CD200; My033; OX2; CD200 molecule; MRC; OX-2

Clonality

Monoclonal

Clone

OX-104

Conjugation

None (AF/LE)

Applications

FCM

Field of Research

Immunology; Cardiovascular

Purification

>98%, Protein A/G purified

Concentration

≥ 1 mg/mL

Dilution

Buffer

Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.

Shipping Conditions

Ice bag

Storage Conditions

Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.