Native Mouse Alpha-2-Macroglobulin

<strong>Native Mouse Alpha-2-Macroglobulin</strong>_x000D_ <strong>Catalog number:</strong> B2018755_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 100 µg_x000D_ <strong>Molecular Weight or Concentration:</strong> N/A_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> ‚àí20¬∞C_x000D_ <strong>Keywords:</strong> Alpha-2-macroglobulin-P, A2m, A2mp_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MŒ©-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Jensen PE, Shanbhag VP, Stigbrand T. Methanethiolation of the liberated cysteine residues of human alpha 2-macroglobulin treated with methylamine generates a derivative with similar functional characteristics as native alpha 2-macroglobulin Eur J Biochem. 1995 Feb 1;227(3):612-6._x000D_ 2: Hudson NW, Koo PH. Subunit and primary structure of a mouse alpha-macroglobulin, a human alpha 2-macroglobulin homologue Biochim Biophys Acta. 1982 Jun 4;704(2):290-303._x000D_ 3: LaMarre J, Hayes MA, Wollenberg GK, Hussaini I, Hall SW, Gonias SL. An alpha 2-macroglobulin receptor-dependent mechanism for the plasma clearance of transforming growth factor-beta 1 in mice J Clin Invest. 1991 Jan;87(1):39-44._x000D_ 4: Zucker S, Lysik RM, Zarrabi MH, Fiore JJ, Strickland DK. Proteinase-alpha 2 macroglobulin complexes are not increased in plasma of patients with cancer Int J Cancer. 1991 May 30;48(3):399-403._x000D_ 5: Willingham MC, Maxfield FR, Pastan IH. alpha 2 Macroglobulin binding to the plasma membrane of cultured fibroblasts. Diffuse binding followed by clustering in coated regions J Cell Biol. 1979 Sep;82(3):614-25._x000D_ 6: Webb DJ, Gonias SL. A modified human alpha 2-macroglobulin derivative that binds tumor necrosis factor-alpha and interleukin-1 beta with high affinity in vitro and reverses lipopolysaccharide toxicity in vivo in mice Lab Invest. 1998 Aug;78(8):939-48._x000D_ 7: Wolf BB, Gonias SL. Neurotrophin binding to human alpha 2-macroglobulin under apparent equilibrium conditions Biochemistry. 1994 Sep 20;33(37):11270-7._x000D_ 8: Misra UK, Chu CT, Rubenstein DS, Gawdi G, Pizzo SV. Receptor-recognized alpha 2-macroglobulin-methylamine elevates intracellular calcium, inositol phosphates and cyclic AMP in murine peritoneal macrophages Biochem J. 1993 Mar 15;290 ( Pt 3)(Pt 3):885-91._x000D_ 9: Wollenberg GK, LaMarre J, Rosendal S, Gonias SL, Hayes MA. Binding of tumor necrosis factor alpha to activated forms of human plasma alpha 2 macroglobulin Am J Pathol. 1991 Feb;138(2):265-72._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/2464277">10: Hoffman M, Pizzo SV, Weinberg JB. Alpha 2 macroglobulin-proteinase complexes stimulate prostaglandin E2 synthesis by peritoneal macrophages Agents Actions. 1988 Dec;25(3-4):360-7. </a>_x000D_ _x000D_ <strong>Products Related to Native Mouse Alpha-2-Macroglobulin can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>