Shegansu B
Shegansu B is an inhibitor of IL-1β. Shegansu B 6 inhibits IL-1β expression on LPS-induced THP-1 cells with 64.74% inhibition. Shegansu B has anti-inflammatory activity[1].
Product Specifications
CAS Number
291535-65-4
Product Name Alternative
(+) -Shegansu B; Parvifolol D
UNSPSC
12352005
Target
Interleukin Related
Type
Natural Products
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/shegansu-b.html
Solubility
10 mM in DMSO
Smiles
COC1=C2C([C@@](C3=CC(O)=CC(O)=C3)([H])[C@](C(C=C4)=CC(OC)=C4O)([H])O2)=CC(/C=C/C5=CC(O)=CC(O)=C5)=C1
Molecular Formula
C30H26O8
Molecular Weight
514.52
References & Citations
[1]Tian LW, et al. A new dimeric stilbene from the lianas of Gnetum parvifolium. Nat Prod Res. 2017 Jul;31 (13) :1495-1500.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
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