R- (-) -Oxaprotiline

R- (-) -Oxaprotiline (Levoprotiline) is an antidepressant with anticholinergic and sympathostimulatory activities. R- (-) -Oxaprotiline exhibits different abilities to block norepinephrine uptake and anticholinergic activity compared to its enantiomer C 49802 B-Ba. R- (-) -Oxaprotiline in human studies shows physiological effects consistent with those in animals. Administration of R- (-) -Oxaprotiline results in a modest increase in heart rate and arterial blood pressure. Salivation is inhibited with R- (-) -Oxaprotiline, consistent with its anticholinergic properties. R- (-) -Oxaprotiline has similar effects to the established antidepressant compound Levoprotiline and has a shorter onset of action[1].