Arnicolide D
Product Specifications
UNSPSC Description
Arnicolide D is a sesquiterpene lactone isolated from Centipeda minima. Arnicolide D modulates the cell cycle, activates the caspase signaling pathway and inhibits the PI3K/AKT/mTOR and STAT3 signaling pathways. Arnicolide D inhibits Nasopharyngeal carcinoma (NPC) cell viability in a concentration- and time-dependent manner[1].
Target Antigen
Akt; Caspase; mTOR; PI3K; STAT
Type
Natural Products
Related Pathways
Apoptosis;JAK/STAT Signaling;PI3K/Akt/mTOR;Stem Cell/Wnt
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/arnicolide-d.html
Purity
99.20
Solubility
DMSO : 25 mg/mL (ultrasonic)
Smiles
CC(C(O[C@H]1[C@@]([C@@H]2C)([H])[C@@](OC2=O)([H])C[C@@H](C)[C@@]3([H])[C@]1(C(C=C3)=O)C)=O)=C
Molecular Weight
332.39
References & Citations
[1]Liu R, et al. Arnicolide D, from the herb <i>Centipeda minima</i>, Is a Therapeutic Candidate against Nasopharyngeal Carcinoma. Molecules. 2019 May 17;24(10).
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-N6843/Arnicolide-D-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-N6843/Arnicolide-D-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
34532-68-8
Available Sizes
Curated Selection
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