KRAS inhibitor-25
KRAS inhibitor-25 (compound 151a) is a pyridopyrimidine KRAS inhibitor, with an IC50 of [1].
Product Specifications
CAS Number
3030577-05-7
UNSPSC
12352005
Target
Ras
Type
Reference compound
Related Pathways
GPCR/G Protein; MAPK/ERK Pathway
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/kras-inhibitor-25.html
Smiles
FC(C(C1=C(CCCCCC2)C(Cl)=CC(O)=C1)=NC=C34)=C3N=C(OC[C@]56N(C[C@H](F)C6)CCC5)N=C4N7CC2(O)CCC7
Molecular Formula
C32H38ClF2N5O3
Molecular Weight
614.13
References & Citations
[1]James Paul LAJINESS, et al. Pyridopyrimidine kras inhibitors. Patent WO 2024/040131 A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
K-Ras
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