9- (β-D-Xylofuranosyl) adenine

9- (β-D-Xylofuranosyl) adenine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277) [1].

Product Specifications

CAS Number

[524-69-6]

UNSPSC

12352005

Target

Nucleoside Antimetabolite/Analog

Type

Oligonucleotides

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/9-β-d-xylofuranosyl-adenine.html

Purity

99.92

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

OC[C@@H]1[C@H](O)[C@@H](O)[C@H](N2C(N=CN=C3N)=C3N=C2)O1

Molecular Formula

C10H13N5O4

Molecular Weight

267.24

References & Citations

[1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18 (23) :3373-88.|[2]Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26 (6) :1490-1500.