11-epi-Chaetomugilin I
11-epi-Chaetomugilin I is a metabolite found in Chaetomium globosum. 11-epi-Chaetomugilin I exhibits significant cytotoxic activity against the murine P388 leukemia cell line, the human HL-60 leukemia cell line, the murine L1210 leukemia cell line, and the human KB epidermoid carcinoma cell line[1].
Product Specifications
CAS Number
[1319729-88-8]
UNSPSC
12352005
Target
Endogenous Metabolite
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/11-epi-chaetomugilin-i.html
Solubility
10 mM in DMSO
Smiles
O=C(/C(C)=C/C)C[C@H]([C@@]1(O)C)C2=COC(/C=C/[C@H](C)[C@H](O)C)=CC2=C(C1=O)Cl
Molecular Formula
C22H27ClO5
Molecular Weight
406.90
References & Citations
[1]Yamada T, et al. New class azaphilone produced by a marine fish-derived Chaetomium globosum. The stereochemistry and biological activities. Bioorg Med Chem. 2011;19 (13) :4106-4113.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
Microbial Metabolite
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