Rabbit anti Human NUMB

Product Specifications

Background

Implicated in the control of cell fate decisions during development. Interacts with EPS15, LNX and NOTCH1. May interact with DUOXA1. Interacts with RALBP1 in a complex also containing EPN1 and TFAP2A during interphase and mitosis.

CAS Number

9007-83-4

Synonyms

Protein S171, Protein numb homolog

UniProt

P49757 (Human)

Host

Rabbit

Species Reactivity

Human

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

Purification Method

Ammonium Sulfate Precipitation

Assay Principle

Antibody can be used for Western blotting (1-5 µg/mL). Optimal concentration should be evaluated by serial dilutions.

Stability

See expiration date on vial

Concentration

See vial for Concentration

Form

Provided as solution in phosphate buffered saline with 0,08% sodium azide

Precautions

This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving Humans or animals.

References & Citations

1. Susini, L., et al. 'Siah-1 binds and regulates the function of Numb.; Proc. Natl. Acad. Sci. U.S.A. 98:15067-15072(2001). 2. Verdi, J.M., et al. 'Distinct Human NUMB isoforms regulate differentiation vs. proliferation in the neuronal lineage.; Proc. Natl. Acad. Sci. U.S.A. 96:10472-10476(1999).