Tauro-α-muricholic acid

Tauro-alpha-muricholic acid (T-alpha-MCA) is a bile acid that belongs to a class of compounds that are synthesized in the liver and play an important role in the digestive process. Tauro-α-muricholic acid activates Farni X receptors (FXR) which are involved in the regulation of bile acid synthesis, metabolism and transport. Tauro-alpha-muricholic acid can be used in the study of metabolic syndrome and cardiovascular disease[1].

Product Specifications

CAS Number

[25613-05-2]

Product Name Alternative

T-α-MCA

UNSPSC

12352211

Target

Endogenous Metabolite; FXR

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Metabolic Disease; Cardiovascular Disease; Others

Assay Protocol

https://www.medchemexpress.com/tauro-α-muricholic-acid.html

Purity

99.18

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

C[C@@H]([C@H]1CC[C@]2([C@@]3([C@@H]([C@H]([C@@]4(C[C@@H](CC[C@@]4([C@]3(CC[C@]12C)[H])C)O)[H])O)O)[H])[H])CCC(NCCS(=O)(O)=O)=O

Molecular Formula

C26H45NO7S

Molecular Weight

515.70

References & Citations

[1]FUJIHIRA E, et al. A new solvent system for thin-layer chromatographical separation of taurine-conjugated trihydroxy bile acids in rat bile[J]. Chemical and Pharmaceutical Bulletin, 1972, 20 (12) : 2719-2721.