(S, R, S) -AHPC-NHCO-C-O-C5-N3

(S, R, S) -AHPC-NHCO-C-O-C5-N3 is a conjugate of ligand for E3 ligase (HY-125845) and linker (HY-161792) . (S, R, S) -AHPC-NHCO-C-O-C5-N3 can be utilized for synthesis of PROTAC SARS-CoV-2 Mpro degrader-3 (HY-161789) [1].

Product Specifications

CAS Number

[2816967-28-7]

UNSPSC

12352005

Target

E3 Ligase Ligand-Linker Conjugates

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/s-r-s-ahpc-nhco-c-o-c5-n3.html

Smiles

O=C(COCCCCCN=[N+]=[N-])N[C@H](C(N1C[C@@H](C[C@H]1C(NCC2=CC=C(C=C2)C3=C(N=CS3)C)=O)O)=O)C(C)(C)C

Molecular Formula

C29H41N7O5S

Molecular Weight

599.74

References & Citations

[1]Cheng S, et al., Development of novel antivrial agents that induce the degradation of the main protease of human-infecting coronaviruses. Eur J Med Chem. 2024 Jun 25;275:116629.