(S, R, S) -AHPC-NHCO-C-O-C5-N3
(S, R, S) -AHPC-NHCO-C-O-C5-N3 is a conjugate of ligand for E3 ligase (HY-125845) and linker (HY-161792) . (S, R, S) -AHPC-NHCO-C-O-C5-N3 can be utilized for synthesis of PROTAC SARS-CoV-2 Mpro degrader-3 (HY-161789) [1].
Product Specifications
CAS Number
[2816967-28-7]
UNSPSC
12352005
Target
E3 Ligase Ligand-Linker Conjugates
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/s-r-s-ahpc-nhco-c-o-c5-n3.html
Smiles
O=C(COCCCCCN=[N+]=[N-])N[C@H](C(N1C[C@@H](C[C@H]1C(NCC2=CC=C(C=C2)C3=C(N=CS3)C)=O)O)=O)C(C)(C)C
Molecular Formula
C29H41N7O5S
Molecular Weight
599.74
References & Citations
[1]Cheng S, et al., Development of novel antivrial agents that induce the degradation of the main protease of human-infecting coronaviruses. Eur J Med Chem. 2024 Jun 25;275:116629.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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