Purified Anti-Human CD27 Antibody[O323]

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor.

S152. LPFS; T-cell activation antigen CD; TNFRSF; S152.LPFS; CD27; S152; S152. LPFS2; T14; TNFRSF7; Tp55; S152.LPFS2; CD27L receptor; T-cell activation antigen CD27; S152; TNFRSF7; CD 27; CD27 antigen; CD27 molecule; LPFS2; MGC20393; OTTHUMP00000238557; T cell activation antigen CD27; T cell antivation antigen S152; TNFRSF 7; TNFSF7; Tp 55; Tumor necrosis factor receptor superfamily member 7