Anti-Hu CD245 Purified
CD245 is a 220-250 kDa transmembrane protein of unknown structure. It is expressed at lower level on resting blood lymphocytes, granulocytes, platelets, and thymocytes, and at high level on monocytes and on IL-2-dependent T cell lines. It is also expressed on Ewing sarcoma and osteosarcoma cell lines. CD245 seems to act as a costimulation molecule of T and NK cells.
Product Specifications
Certification
RUO
Reactivity
Human
Immunogen
Human NK-type YT2C2 cells
Target Antigen
CD245
Clone
DY12
Applications
WB, FC (QC tested), IHC, IP
Concentration
1 mg/mL
Format
Purified
Buffer
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
References & Citations
*Kishimoto et al.: Leucocyte typing VI, Garland Publishing 1996, URL: , *Mason et al.: Leucocyte typing VII, Oxford University Press 2000, URL:
Storage Conditions
Store at 2-8°C. Do not freeze.
Specificity
Applications Notes
Flow cytometry: Recommended dilution: 1-5 μg/ml.
Isotype
Mouse IgG1 kappa
Frequently Asked Questions
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