(±) -Perillaldehyde
(±) -Perillaldehyde has an antidepressant effect by modulating the olfactory nervous system in a mouse model of stress-induced depression. (±) -Perillaldehyde also has anti-inflammatory activity, inducing JNK activation in RAW264.7 cells and inhibiting the expression of TNF-α, with an IC50 of 171.7 μM[1][2].
Product Specifications
CAS Number
2111-75-3
UNSPSC
12352211
Hazard Statement
H315, H319, H335
Target
JNK; TNF Receptor
Type
Reference compound
Related Pathways
Apoptosis; MAPK/ERK Pathway
Field of Research
Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/racemic-perillaldehyde.html
Purity
96.70
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CC(C1CCC(C=O)=CC1)=C
Molecular Formula
C10H14O
Molecular Weight
150.22
Precautions
H315, H319, H335
References & Citations
[1]N Ito, et al. Antidepressant-like Effect of l-perillaldehyde in Stress-induced Depression-like Model Mice through Regulation of the Olfactory Nervous System. Evid Based Complement Alternat Med. 2011:2011:512697.|[2]Takuya Uemura, et al. Intestinal Anti-Inflammatory Activity of Perillaldehyde. J Agric Food Chem. 2018 Apr 4;66 (13) :3443-3448.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
LC400828 20 µg
Lymphocyte Activation Gene 3 (LAG3) (NM_002286) Human Over-expression Lysate
Sign In for Pricing
View Details 
BNUB0972-500 1x 500 µL
Myeloid-Associated Differentiation Marker (MYADM/972), 0.2mg/mL
Sign In for Pricing
View Details 
BNCB2008-100 1x 100 µL
IL-4 (Interleukin-4), Mouse (11B11), Biotin conjugate, 0.1mg/mL
Sign In for Pricing
View Details 