(±) -Perillaldehyde
(±) -Perillaldehyde has an antidepressant effect by modulating the olfactory nervous system in a mouse model of stress-induced depression. (±) -Perillaldehyde also has anti-inflammatory activity, inducing JNK activation in RAW264.7 cells and inhibiting the expression of TNF-α, with an IC50 of 171.7 μM[1][2].
Product Specifications
CAS Number
2111-75-3
UNSPSC
12352211
Hazard Statement
H315, H319, H335
Target
JNK; TNF Receptor
Type
Reference compound
Related Pathways
Apoptosis; MAPK/ERK Pathway
Field of Research
Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/racemic-perillaldehyde.html
Purity
96.70
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CC(C1CCC(C=O)=CC1)=C
Molecular Formula
C10H14O
Molecular Weight
150.22
Precautions
H315, H319, H335
References & Citations
[1]N Ito, et al. Antidepressant-like Effect of l-perillaldehyde in Stress-induced Depression-like Model Mice through Regulation of the Olfactory Nervous System. Evid Based Complement Alternat Med. 2011:2011:512697.|[2]Takuya Uemura, et al. Intestinal Anti-Inflammatory Activity of Perillaldehyde. J Agric Food Chem. 2018 Apr 4;66 (13) :3443-3448.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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