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LIFR Recombinant Rabbit Monoclonal Antibody [PSH08-76]

LIFR also known as CD118 (Cluster of Differentiation 118), is a subunit of a receptor for leukemia inhibitory factor. The leukemia inhibitory factor (LIF) is a polyfunctional cytokine that affects the differentiation, survival, and proliferation of a wide variety of cells in the adult and the embryo. LIF action appears to be mediated through a high-affinity receptor complex composed of a low-affinity LIF binding chain (LIF receptor) and a high-affinity converter subunit, glycoprotein 130 (IL6ST, gp130). Both LIFR and gp130 are members of a family of cytokine receptors that includes components of the receptors for the majority of hematopoietic cytokines and for cytokines that affect other systems, including the ciliary neurotrophic factor, growth hormone and prolactin.

Product Specifications

CAS Number

9000-83-3

Product Name Alternative

CD118 antibody CD118 antigen antibody FLJ98106 antibody FLJ99923 antibody Leukemia inhibitory factor receptor alpha antibody Leukemia inhibitory factor receptor antibody LIF R antibody LIF receptor antibody LIF-R antibody Lifr antibody LIFR_HUMAN antibody SJS2 antibody STWS antibody SWS antibody

Abbreviation

Leukemia inhibitory factor receptor LIF receptor; LIF-R CD118 LIFR

Swiss Prot

P42702 Human

Cellular Locus

Cell membrane.

Host

Rabbit

Species Reactivity

Human

Immunogen

Recombinant protein within human LIFR aa 1-850.

Isotype

IgG

Clone

PSH08-76

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB

Positive Control

HeLa cell lysate, PANC-1 cell lysate, MDA-MB-231 cell lysate, HCT 116 cell lysate, RD cell lysate.

Concentration

1 mg/mL

Dilution

WB: 1:2,000

Purity

Protein A affinity purified.

Form

Liquid

Buffer

PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 124 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

Yes

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