LIFR Recombinant Rabbit Monoclonal Antibody [PSH08-76]
LIFR also known as CD118 (Cluster of Differentiation 118), is a subunit of a receptor for leukemia inhibitory factor. The leukemia inhibitory factor (LIF) is a polyfunctional cytokine that affects the differentiation, survival, and proliferation of a wide variety of cells in the adult and the embryo. LIF action appears to be mediated through a high-affinity receptor complex composed of a low-affinity LIF binding chain (LIF receptor) and a high-affinity converter subunit, glycoprotein 130 (IL6ST, gp130). Both LIFR and gp130 are members of a family of cytokine receptors that includes components of the receptors for the majority of hematopoietic cytokines and for cytokines that affect other systems, including the ciliary neurotrophic factor, growth hormone and prolactin.
Product Specifications
CAS Number
9000-83-3
Product Name Alternative
Abbreviation
Leukemia inhibitory factor receptor LIF receptor; LIF-R CD118 LIFR
Swiss Prot
P42702 Human
Cellular Locus
Cell membrane.
Host
Rabbit
Species Reactivity
Human
Immunogen
Recombinant protein within human LIFR aa 1-850.
Isotype
IgG
Clone
PSH08-76
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB
Positive Control
HeLa cell lysate, PANC-1 cell lysate, MDA-MB-231 cell lysate, HCT 116 cell lysate, RD cell lysate.
Concentration
1 mg/mL
Dilution
WB: 1:2,000
Purity
Protein A affinity purified.
Form
Liquid
Buffer
PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 124 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes
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