ALP/Carbonic anhydrase-IN-1
ALP/Carbonic anhydrase-IN-1 (Compound 1e) is a dual carbonic anhydrase (CA) and alkaline phosphatase (ALP) inhibitor. ALP/Carbonic anhydrase-IN-1 shows IC50 values of 0.44 µM, 1.61 µM, 0.51 µM, and 0.107 µM for CA-II, CA-IX, CA-XII, and ALP, respectively[1].
Product Specifications
CAS Number
[2091887-74-8]
UNSPSC
12352005
Target
Carbonic Anhydrase; Phosphatase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/alp-carbonic-anhydrase-in-1.html
Purity
99.90
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CCCCC1=CC2=C(N=CC=C2)N3C=CC=C13
Molecular Formula
C15H16N2
Molecular Weight
224.30
References & Citations
[1]Salman Alrokayan, et al. [1, 8]-Naphthyridine derivatives as dual inhibitor of alkaline phosphatase and carbonic anhydrase. BMC Chem. 2023 Oct 25;17 (1) :142.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CA II; CA IX; CA XII
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS6364308-01 0.1 mL
YIPF5, NT (YIPF5, FINGER5, YIP1A, Protein YIPF5, Five-pass transmembrane protein localizing in the Golgi apparatus and the endoplasmic reticulum 5, Smooth muscle cell-associated protein 5, YIP1 family member 5, YPT-interacting protein 1 A) (MaxLight 405)
Ask
View Details 
MBS6364308-02 5x 0.1 mL
YIPF5, NT (YIPF5, FINGER5, YIP1A, Protein YIPF5, Five-pass transmembrane protein localizing in the Golgi apparatus and the endoplasmic reticulum 5, Smooth muscle cell-associated protein 5, YIP1 family member 5, YPT-interacting protein 1 A) (MaxLight 405)
Ask
View Details 
488832 100 µL
PLEKHG6 (Pleckstrin Homology Domain-Containing Family G Member 6, Pleckstrin Homology and RhoGEF Domain Containing G6)
Ask
View Details 