ALP/Carbonic anhydrase-IN-1

ALP/Carbonic anhydrase-IN-1 (Compound 1e) is a dual carbonic anhydrase (CA) and alkaline phosphatase (ALP) inhibitor. ALP/Carbonic anhydrase-IN-1 shows IC50 values of 0.44 µM, 1.61 µM, 0.51 µM, and 0.107 µM for CA-II, CA-IX, CA-XII, and ALP, respectively[1].

Product Specifications

CAS Number

[2091887-74-8]

UNSPSC

12352005

Target

Carbonic Anhydrase; Phosphatase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/alp-carbonic-anhydrase-in-1.html

Purity

99.90

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

CCCCC1=CC2=C(N=CC=C2)N3C=CC=C13

Molecular Formula

C15H16N2

Molecular Weight

224.30

References & Citations

[1]Salman Alrokayan, et al. [1, 8]-Naphthyridine derivatives as dual inhibitor of alkaline phosphatase and carbonic anhydrase. BMC Chem. 2023 Oct 25;17 (1) :142.