ALP/Carbonic anhydrase-IN-1
Product Specifications
UNSPSC Description
ALP/Carbonic anhydrase-IN-1 (Compound 1e) is a dual carbonic anhydrase (CA) and alkaline phosphatase (ALP) inhibitor. ALP/Carbonic anhydrase-IN-1 shows IC50 values of 0.44 µM, 1.61 µM, 0.51 µM, and 0.107 µM for CA-II, CA-IX, CA-XII, and ALP, respectively[1].
Target Antigen
Carbonic Anhydrase; Phosphatase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/alp-carbonic-anhydrase-in-1.html
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CCCCC1=CC2=C(N=CC=C2)N3C=CC=C13
Molecular Weight
224.30
References & Citations
[1]Salman Alrokayan, et al. [1, 8]-Naphthyridine derivatives as dual inhibitor of alkaline phosphatase and carbonic anhydrase. BMC Chem. 2023 Oct 25;17(1):142.
Shipping Conditions
Blue Ice
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-157139/ALP-Carbonic-anhydrase-IN-1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-157139/ALP-Carbonic-anhydrase-IN-1-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
2091887-74-8
Available Sizes
Curated Selection
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