HBChE-IN-3
HBChE-IN-3 (compound 30) is a combination of carbonic anhydrase (CA) activator and cholinesterase (ChE) inhibitor with IC50 values of 7.4 and 1.9 nM for AchE and BchE, respectively. hBChE-IN-3 can be used in the study of neurodegeneration and psychiatric disorders[1].
Product Specifications
UNSPSC
12352005
Target
Carbonic Anhydrase; Cholinesterase (ChE)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/hbche-in-3.html
Smiles
O=C([C@H](CC1=CC=CC=C1)N)NCCCCCNC2=C3CCCCC3=NC4=CC=CC=C42
Molecular Formula
C27H34N4O
Molecular Weight
430.59
References & Citations
[1]Nocentini A, et al. Enhanced Recognition Memory through Dual Modulation of Brain Carbonic Anhydrases and Cholinesterases. J Med Chem. 2024 Sep 26;67 (18) :16873-16898.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
AChE; BChE
Frequently Asked Questions
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