HBChE-IN-3

HBChE-IN-3 (compound 30) is a combination of carbonic anhydrase (CA) activator and cholinesterase (ChE) inhibitor with IC50 values of 7.4 and 1.9 nM for AchE and BchE, respectively. hBChE-IN-3 can be used in the study of neurodegeneration and psychiatric disorders[1].

Product Specifications

UNSPSC

12352005

Target

Carbonic Anhydrase; Cholinesterase (ChE)

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/hbche-in-3.html

Smiles

O=C([C@H](CC1=CC=CC=C1)N)NCCCCCNC2=C3CCCCC3=NC4=CC=CC=C42

Molecular Formula

C27H34N4O

Molecular Weight

430.59

References & Citations

[1]Nocentini A, et al. Enhanced Recognition Memory through Dual Modulation of Brain Carbonic Anhydrases and Cholinesterases. J Med Chem. 2024 Sep 26;67 (18) :16873-16898.